碳纳米管（CNTs）具有优异的性能，被广泛应用于材料、生物、催化和电子等多个领域。由多个苯环对位连接而成的环对苯撑（Cycloparaphenylenes, CPPs）被认为是扶手椅型碳纳米管（CNTs）最简单的基元，开发手性CPP大环能为自下而上合成手性碳纳米管提供可能，因此备受科学家的关注。目前，构建手性大环主要有两种方式，一是引入非手性基元，利用空间位阻限制破坏大环本身高度对称性，形成固有手性；二是直接引入手性基元。已报道的大部分手性大环均是在CPP环进行芳构化之前就引入了构建基元。在本课题中，我们设计了一种新型手性CPP大环，选取了经典的甲氧基修饰的环己二烯单元作为前体，将氧化噻吩结构引入CPP骨架中，通过Diels-Alder后修饰反应，引入手性基元，从而制备具有R*基取代的邻苯二甲酰亚胺结构的大环，为合成多样手性基团的大环化合物提供便利，也为后续研究提供备选材料和新思路。

Carbon nanotubes (CNTs) having excellent properties are widely used in many fields, such as materials, biology, catalysis and electronics. Cycloparaphenylenes (CPPs) formed by para-position connection of several benzene rings are considered as the simplest structural units of armchair carbon nanotubes. The development of chiral CPP macrocycles can provide the possibility for the bottom-up synthesis of chiral carbon nanotubes, attracting the attention of scientists. At present, there are two main ways to construct chiral macrocycles: one is to introduce achiral units, destroying the high symmetry of macrocycles by steric hindrance to construct inherent chirality; the other is to introduce chiral units directly. For many reported chiral macrocycles, building units are introduced before the aromatization reaction of CPP macrocycles. Herein, we design a new chiral macrocycle based on CPPs structures. We select the classical methoxy-modified cyclohexadiene units as precursors, introducing the thiophene 1,1-dioxide into the CPP skeleton. Then we try to introduce chiral units through Diels-Alder post-modification reaction, in order to synthesizing the macrocycle with N-R* phthalimide backbone. The research can facilitate the synthesis of macrocycles with various chiral groups and provide alternative materials and new ideas for the following research.