稀土离子掺杂的上转换发光纳米材料NaYF4:Yb,Er是一种新型的具有应用潜力的生物荧光标记材料。与传统材料相比，它具有大的反Stokes位移，窄的发射谱带和低生物毒性等显著优点。而要使NaYF4:Yb,Er真正应用于生物荧光标记领域，其发光效率还有待提高。本论文尝试构筑NaYF4:Yb,Er与Ag纳米粒子的复合结构，利用金属表面发光增强效应增强NaYF4:Yb,Er的发光。 本论文首先利用有机溶剂前驱体热分解法合成了单分散性较好的α相NaYF4:Yb, Er和β相NaYF4:Yb, Er纳米晶；在油胺/十八烯体系中，以AgNO3为前驱体合成了Ag纳米颗粒，并对其颗粒大小和单分散性进行了调控。 对于复合结构，本论文通过MUA（11-巯基十一烷酸）作为连接剂成功实现了NaYF4:Yb,Er与Ag纳米颗粒的连接，并对该方法进行了条件优化。

NaYF4:Yb,Er upconversion nanocrystals show great potential application as biological labels, which is attributed to its large anti-Stokes shift, narrow emission bands and low biological toxicity. However, low luminous efficiency hindered its application in the biological sciences. In this thesis, we tried to fabricate NaYF4:Yb,Er-Ag hybrid structure to enhance the upconversion luminescence. Firstly, monodispersed α-NaYF4:Yb,Er and β-NaYF4:Yb,Er were synthesized through the pyrolysis method. And Ag nanoparticles were synthesized using AgNO3 as precursor in oleylamine and 1-octadecene solution, the size distribution was controlled by adjust the reaction time and temperature. Then, NaYF4:Yb,Er-Ag hybrid structure was successfully synthesized using MUA（11-mercaptoundecanoic acid）as crosslinker, and the reaction conditions has been optimized. Keywords: upconversion emission, NaYF4:Yb,Er, Ag nanoparticles, hybrid structure