在人类媒介传播史上，每一次新媒介的出现，都会带来一次传播方式的重大变革。手机的出现，影响并改变着人类社会生活的方方面面。如果说过去的十多年中，互联网改变了人类社会，那么今后十年，手机也会改变人们的生活及媒体产业布局。本文通过对《人民日报》手机报在08年汶川大地震、08年北京奥运会、09年六十周年国庆及09年和10年两会所出特刊的内容分析，结合议程设置理论，试图研究以手机为载体的报纸内容与传统报纸内容在议程设置上的差异和对人们思维方式的影响，探索其原因和未来发展方向。本论文主要分为三章，第一章是研究概述，介绍“二次议程设置”与“大事件”概念的阐释和界定，在新媒体环境下二次议程设置功能出现的必然性，对手机报的概念进行了梳理、并归纳总结了手机报的种类、发展现状。第二章采用比较分析、内容分析等方法，用具体的事例分析在大事件的背景下二次议程设置理论传播的特点。第三章结合手机报特刊内容，分析二次议程设置上的新走向，此外还分析了手机报与传统报纸的互动融合是一种必然的发展趋势。这种相互间的融合是媒介间互动的一种必然趋势，传统报纸借力于手机这个新平台，应该要在内容上多加创新，互补升级，这才是传统媒介与新媒体融合的主旋律。

On the history of human vector-borne, each time when a new media appears, it will bring a major change in the transmission method. The emergence of mobile phones affects and changes all aspects of human social life. If it is said that internet has changed human society in the past 10 years, then mobile phone will also change people's lives and the layout of the media industry in the next 10 years. Through the analysis on the content of some major events in People's Daily mobile news with agenda setting theory, this paper tries to research the differences between agenda setting of mobile news content and traditional newspapers and the impact on thought way of people, And, the thesis explores the cause and development direction in the future. The paper is mainly divided into three sections. The first one is a research overview which introduces the definition of secondary agenda setting and events. This part shows the necessity of secondary agenda setting arise in the new media environment and concludes the kinds and development situation of mobile news. By the method of comparative analysis and content analysis, the second segment uses concrete examples to analysis the features of the secondary agenda setting theory communication in big events. Combining with special report on mobile news, the last chapter analyzes the new trend of secondary agenda setting. In addition, it also analyzes that the interaction fusion of the traditional newspaper and phone paper is an inevitable trend. This interaction fusion is an inevitable trend between the media convergence. With new phone platform, traditional newspapers should innovate in content and help each other. This is the main theme on convergence of traditional media and new media.