场馆科学学习是非正式学习的重要方式之一，对终身学习和生物教学都具有重要意义。为减少“走马观花一日游式”的场馆参观，引导参观者在有趣的学习活动中深入理解相关的生物学概念，本研究以中国科学技术馆的同源器官展品为例将微信H5作为学习平台设计了一个学习活动。此学习活动基于中国普通高中生物课程标准、美国NGSS以及中国学生发展核心素养中的相关要求设定学习目标，针对在学习过程中存在的错误概念，使用5E教学模式进行了学习活动的设计。 基于微信H5平台的学习活动设计完成之后，针对学习活动的科学性、教育性、技术性、使用效果和整体感受，设计了调查问卷并使用问卷星对场馆参观者、一线教师、职前教师等群体进行了线上和线下调研。基于对调研数据的分析，本研究认为基于微信开展场馆科学学习是具有可行性的。 此外，针对调查过程中收集到的意见和建议，本研究还对第一版学习活动进行了修改和完善，并对这一学习活动未来的发展方向做了规划。

The museum-based science learning is one of the important ways of informal learning, which has an important significance for lifelong learning and biology teaching. In order to reduce the museum visit form that is “a day trip with a quick glance”, and guide the visitors to understand related biological concepts deeply in the interesting learning activities, this thesis took the exhibits named Homologous Organ in the China Science and Technology Museum as an example, and used WeChat H5 as a learning platform to design a learning activity. This learning activity is based on the relevant requirements of the Chinese ordinary high school biology curriculum standard, American NGSS and Chinese students develop core literacy to set learning goals, and it aims at students’ misconceptions in the learning process, then use the "5E" model of teaching content to design learning activities. After designed the learning activity based on the WeChat H5 platform, this thesis designed a questionnaire aims to the learning activities’ scientific, educational, technical, use effect and overall feeling, and then used the SO JUPM to investigate visitors, teachers, pre-service teachers and other groups through online and offline. The questionnaire. Based on the analysis of survey data, this thesis considered that using WeChat for the museum-based science learning is feasible. In addition, according to the opinions and suggestions collected during the investigation, this thesis modified and perfected the first edition of learning activity, and made a plan for the development direction of the learning activity in the future.