《非正式会谈》作为近年来跨文化访谈节目的典型，始终实践着以汉语为载体的世界文化交流和中国文化传播。节目以汉语为交流沟通的媒介和载体，在议题的选取上也周密涵盖了世界各国涉及和值得讨论的问题，同时有着很好的汉化处理。在为世界各国文化的交流与碰撞提供平台的同时，也兼顾了中国文化的良性沟通和输出。在《非正式会谈》所涉及的议题中，主要有人际交往类、文化习俗类、社会类、娱乐类、教育类、经济类、工作/职业类、医疗科技类、环境/动物类九个类型。议题的选取呈现出以本土化为宗旨、包容性与争议性并存的特点。本论文通过对议题设置的探讨，分析其议题特点，设置意图，并挖掘其中反映出的跨文化传播内涵。并从《非正式会谈》议题设置中得出对跨文化传播启示。

Informal Talks, as a typical cross-cultural interview program in recent years, has always been practicing world cultural exchange and Chinese cultural communication with Chinese as the carrier. The program takes Chinese as the medium and carrier of communication and communication, and the selection of issues also carefully covers the issues involved and worthy of discussion in various countries around the world, while having a good Sinicization treatment. While providing a platform for the exchange and collision of cultures around the world, it also takes into account the benign communication and output of Chinese culture. In the topics involved in Informal Talks, there are mainly nine types: interpersonal communication, cultural customs, society, entertainment, education, economy, work/occupation, medical technology, environment/animal. The selection of issues presents the characteristics of coexistence of inclusiveness and controversy with localization as the purpose. Through the discussion of the topic setting, this paper analyzes the characteristics of the topic, the intention of setting, and excavates the connotation of cross-cultural communication reflected in it. And draws enlightenment on cross-cultural communication from the topic setting of Informal Talks.