为评估高校在校学生PM_2.5暴露状况及其健康风险， 2016年7月至2018年1月期间，采用细颗粒物采样器OmniFT-mini对北京师范大学校园内七处典型的室内场所（宿舍、教室、图书馆、食堂、机房、体育馆、实验室）进行了PM_2.5浓度监测，招募了学生志愿者佩戴HP2540采样器进行PM_2.5个体暴露样本采样及分析，同期记录了校园附近三处环保监测站点（西城官园、海淀万柳、奥体中心）的室外大气PM_2.5浓度。分析采暖季和非采暖季不同室内场所的PM_2.5浓度特征及其与室外浓度的关系，结合在校学生的日常行为模式调查结果，进行大学生群体在采暖季和非采暖季的PM_2.5暴露评价。收集分析了大量与大气污染物PM_2.5相关的流行病学文献，利用荟萃分析（meta-analysis）方法得到PM_2.5与暴露人群健康效应影响（发病或死亡）的浓度响应参数，进而定量的建立PM_2.5暴露与人群健康效应之间的暴露-反应关系。

结果表明在校大学生PM_2.5个体暴露浓度（均值）分别为采暖季60.20 μg/m³，非采暖季49.27 μg/m³。宿舍、教室等室内场所对个体暴露量有较高的贡献，室内外场所PM_2.5浓度比值（I/O比）在非采暖季高于采暖季，受到通风条件、人员活动及室内场所用途等影响，不同场所的I/O比有一定的差异。Meta分析的结果显示，暴露人群的发病和死亡风险会随着环境中PM_2.5浓度增加而有所上升。PM_2.5浓度每上升10μg/m³时，人群的总死亡率会上升0.71% (95%CI: 0.61%, 0.82%)，总发病率会上升0.79% (95%CI: 0.72%,  0.85%)。长期暴露于采样期间的PM_2.5浓度水平对大学生群体的健康风险为采暖季总死亡率提高0.60% (95%CI: 0.51%, 0.70%)，总发病率提高1.20% (95%CI: 1.07%, 1.34%)；非采暖季总死亡率提高1.06% (95%CI: 0.88%, 1.23%)，总发病率提高2.12% (95%CI: 1.89%, 2.37%)。

In order to assess the exposure and health risk of PM_2.5 for students in Beijing Normal University, PM_2.5 concentration at typical indoor sites and individual exposure concentration (μg/m³) in the campus of Beijing Normal University from July 2016 to January 2018 were sampled and analyzed using the fine particle sampler OmniFT-mini and HP2540 individual sampler, and the atmospheric PM_2.5 concentration of Beijing environmental protection monitoring sites were simultaneously recorded. The characteristics of PM_2.5 concentration at indoor places during heating season and non-heating season and their relationship with outdoor PM_2.5 concentration were analyzed. The exposure concentration of PM_2.5 in the heating season and non-heating season for the students was evaluated by combining with the data of a questionnaire survey on the daily behavior patterns of college students. Many epidemiological studies concerned about PM_2.5 pollution were collected and analyzed to illustrate the relationship between PM_2.5 pollution and people’s health effect.

The results showed that the average individual exposure concentration of PM_2.5 in college students in heating and non-heating season was 60.20 μg/m³ and 49.27 μg/m³, respectively. The indoor environment such as dormitory and classroom had a higher contribution to individual exposure. The indoor and outdoor PM_2.5 concentration ratio (I/O ratio) was higher in the non-heating season than the heating season and varied with the indoor sites, which was thought to be affected by ventilation conditions, personal activities and indoor use. The meta-analysis shows that when PM_2.5 concentration increases, risk of illness and death will also increase. For every 10 μg/m³ increase of PM_2.5, total mortality will increase 0.71% (95%CI: 0.61%, 0.82%), total morbidity will increase 0.79% (95%CI: 0.72%, 0.85%). The impact of long-term exposure to PM_2.5 concentration during the sampling period on university students is that in heating season total mortality will increase 0.60% (95%CI: 0.51%, 0.70%), total morbidity will increase 1.20% (95%CI: 1.07%, 1.34%), and in non-heating season total mortality will increase 1.06% (95%CI: 0.88%, 1.23%), total morbidity will increase 2.12% (95%CI: 1.89%, 2.37%).